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Fig. 5 | Journal of Hematology & Oncology

Fig. 5

From: Decitabine demonstrates antileukemic activity in B cell precursor acute lymphoblastic leukemia with MLL rearrangements

Fig. 5

18F-FDG uptake in spleen is decreased after DEC treatment. a PET/CT was performed on days 21 and 28 in SEM-ffluc xenografts. Representative PET/CT scans demonstrate differences on 18F-FDG uptake. 18F-FDG uptake in spleens of DEC-treated mice was lower than in controls. b 18F-FDG uptake in spleen was calculated for all mice and is expressed as mean [%ID/g] of the metabolic volume. Results are summarized as mean ± SD. The number of analyzed mice for each treatment group is indicated in the bars. c Displayed are representative images of spleen from saline-, DEC- and DEC + AraC-treated group; spleen weight is summarized as mean ± SD

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