Fig. 6

Blast frequency is lower in DEC-treated PDX models. a Analyses of human leukemia cells in BM, spleen, and blood analyzed from PDX mice (patient #159) by flow cytometry. Displayed are representative contour plots from saline (PDX-26)- and DEC (PDX-27)-treated mice. b Displayed is the blast frequency (%CD19⁺ and %CD45⁺) in BM, spleen, and blood of saline (#122: n = 1; #152: n = 2, #159: n = 1)- and DEC (#122: n = 2; #152: n = 2, #159: n = 2)-treated PDX mice