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Fig. 3 | Journal of Hematology & Oncology

Fig. 3

From: STARD13-correlated ceRNA network-directed inhibition on YAP/TAZ activity suppresses stemness of breast cancer via co-regulating Hippo and Rho-GTPase/F-actin signaling

Fig. 3

STARD13-correlated ceRNA network activates Hippo signaling via increasing LATS1/2 expression [1]. a, b Enrichment of signaling signatures differentially expressed (a) and identification of LATS1/2 expression (b) between pLVX-Ctrl and pLVX-STARD13-3′UTR based on RNA-sequencing analysis. c, d LATS1/2 was downregulated when STARD13-correlated ceRNAs were depleted and upregulated when overexpressing STARD13-correlated ceRNAs-3′UTRs in MCF-7 (c) and MDA-MB-231 cells (d). Data were presented as the mean ± SD, n = 3, **p < 0.01 vs. vector or control

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