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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: STARD13-correlated ceRNA network-directed inhibition on YAP/TAZ activity suppresses stemness of breast cancer via co-regulating Hippo and Rho-GTPase/F-actin signaling

Fig. 4

STARD13-correlated ceRNA network activates Hippo signaling via increasing LATS1/2 expression [2]. a, b Western blot analysis of lysates from MDA-MB-231 cells overexpressing STARD13-correlated ceRNAs-3′UTRs (a) and MCF-7 cells depleted of STARD13-correlated ceRNAs (b). c Confocal images showing localization of YAP in MDA-MB-231 cells overexpressing STARD13-correlated ceRNAs-3′UTRs. d Expression of YAP targeting genes in pLVX-Ctrl and pLVX-STARD13-3′UTR cells based on RNA-sequencing analysis. Data were presented as the mean ± SD, n = 3, **p < 0.01 vs. vector or control

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