Fig. 2From: Randomized, phase I/II study of gemcitabine plus IGF-1R antagonist (MK-0646) versus gemcitabine plus erlotinib with and without MK-0646 for advanced pancreatic adenocarcinomaTreatment response within the treatment arms. a Treatment response rates between patients treated with gemcitabine + MK-0646, gemcitabine + MK-0646 + erlotinib, and gemcitabine + erlotinib alone as a part of phase II randomization cohort. b Treatment response rates for all patients treated with gemcitabine + MK-0646 (10Â mg/kg) compared with gemcitabine + MK-0646 (5Â mg/kg) + erlotinib as a part of phase I and II (randomization and expansion) cohorts. G, gemcitabine; M, MK-0646; E, erlotinib; PD, progressive disease; PR, partial response; SD, stable diseaseBack to article page