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Table 1 Patients demographics and clinico-pathological characteristics for phase I and II enrolled pancreatic cancer patients (N = 75)

From: Randomized, phase I/II study of gemcitabine plus IGF-1R antagonist (MK-0646) versus gemcitabine plus erlotinib with and without MK-0646 for advanced pancreatic adenocarcinoma

 

Enrolled patients (N = 75) (%)

Age group

 Median (range)

62.8 (44–83)

 < 60

27 (36%)

 ≥ 60

48 (64%)

Sex

 Male to female ratio

1.7:1

 Female

28 (37.3%)

 Male

47 (62.7%)

Race

 White

61 (81.3%)

 Black

4 (5.3%)

 Hispanic

4 (5.3%)

 Asian

4 (5.3%)

 Others

2 (2.7%)

Tumor differentiation

 Moderate

22 (29.3%)

 Poor

23 (30.7%)

 Unknown

30 (40%)

ECOG

 0

8 (10.7%)

 1

67 (89.3%)

Tumor location

 Head

22 (29.3%)

 Body

32 (42.7%)

 Tail

19 (25.3%)

 Unknown

2 (2.7%)

Site of metastasis

 Liver

61 (75.3%)

 Lung

10 (12.3%)

 Peritoneal

15 (18.5%)

 Others

4 (5.3%)

CA19-9 (U/ml)

 Median (range)

58,159.1 (0.9–58,160)

 ≤ 35

12 (16%)

 > 35

63 (84%)

Previous treatment

 De novo

69 (92%)

 Surgery

4 (4.9%)

 Chemotherapy

4 (4.9%)