Fig. 5
From: Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties
exo-adipocyte-conditioned medium enhances tube formation of HUVECs. a HUVECs were incubated with exo-adipocyte-conditioned medium or adipocyte-conditioned medium for 48 h. The mRNA levels of Ang1, Flk1, Vash1, and TSP1 were evaluated by qRT-PCR. Results are mean ± SD (n = 3 for each group). b Compared with adipocyte-conditioned medium, exo-adipocyte-conditioned medium increased HUVEC tube formation in vitro. Scale bar, 100 μm. Right—representative photograph of tube formation. Left—calculations in three randomly selected fields. Results are mean ± SD (Student’s t test)