Fig. 6

GALNT7 is a target gene of miR-34a in CRC cells. a Sequence alignment of miR-34a with the binding sites in the wild-type and mutant-type regions of GALNT7 was shown. b The negative relevance between miR-34a and GALNT7 expression was revealed by Pearson’s correlation curve. c The relative luciferase activity of 293T cells was tested after co-transfection with GALNT7 wide-type and miR-34a mimic. d GALNT7 level in SW480 cells co-tranfected with SNHG7 and miR-34a mimic was analyzed. e GALNT7 level in SW620 cells co-tranfected with siSNHG7 and miR-34a inhibitor was shown. f, g SNHG7 and GALNT7 competing to bind with miR-34a were identified by function screen analysis in SW480 and SW620 cells. The error bars in graphs represented SD, and each experiment was repeated thrice. *P < 0.05, **P < 0.01