Fig. 2

The effects of Ube2v1 on histone H4 lysine 16 acetylation and expression of Sirt1. a Quantitative mass spectrometry was used to analyze differential proteins between control cells and cells with Ube2v1 stable overexpression. b, c Expression of histone H4 lysine 16 acetylation (H4K16ac) in histone extracts was examined after Ube2v1 was overexpressed (b) or knocked down (c) in SW480 and DLD-1 cells. d, e Sirt1 expression was detected after Ube2v1 was overexpressed (d) or knocked down (e) in SW480 and DLD-1 cells. f The effects of Ube2v1 overexpression on H4K16ac with or without Sirt1 overexpression