Function and clinical significance of circRNAs in solid tumors

Table 2 circRNAs in lung cancer

circBase ID (alias)	Host gene	Putative function	Upregulated/downregulated	miRNA sponge	Target gene/pathway	Reference
hsa_circ_0013958	ACP6	miRNA sponge	Upregulated	miR-134	–	[22]
circ-ITCH	ITCH	miRNA sponge	Downregulated	miR-7, miR-214	Wnt/β-Catenin	[19]
circ-CER	CER	miRNA sponge	Upregulated	miR-136	MMP13	[20]
circ-CER	CER	miRNA sponge	Upregulated	miR-136	MMP13	[21]
hsa_circ_0007385	MEMO1	miRNA sponge	Upregulated	miR-181	–	[24]
hsa_circ_0012673	DHCR24	miRNA sponge	Upregulated	miR-22	ErbB3	[23]
hsa_circ_0014130	PIP5K1A	miRNA sponge*	Upregulated	–	–	[25]
hsa_circ_0000064	B4GALT2	miRNA sponge*	Upregulated	–	MMP-2, MMP-9	[26]

ISSN: 1756-8722