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Table 3 circRNAs in breast cancer

From: Function and clinical significance of circRNAs in solid tumors

circBase ID (alias) Host gene Putative function Upregulated/downregulated miRNA sponge Target gene/pathway Reference
circ-Foxo3 FOXO3 Protein scaffolding Downregulated p53 [32]
circ-Foxo3 FOXO3 miRNA sponge Downregulated miR-22, miR-136, miR-138, miR-149, miR-433, miR-762, miR-3614-5p, miR-3622b-5p [34]
hsa_circ_0008717 ABCB10 miRNA sponge Upregulated miR-1271 [37]
hsa_circ_0001358 SEC62 miRNA sponge* Upregulated ZEB1/2 [28]
hsa_circ_000911 IFNGR2 miRNA sponge Downregulated miR-449a Notch1 [36]
hsa_circ_0001982 RNF111 miRNA sponge Upregulated miR-143 [38]
hsa_circ_0005239 GFRA1 miRNA sponge Upregulated miR-34a GFRA1 [39]
hsa_circ_0006528 PRELID2 miRNA sponge Upregulated miR-7 Raf1 [40]
circ-DENND4C DENND4C Upregulated HIF1α [41]
  1. *Not validated experimentally