Function and clinical significance of circRNAs in solid tumors

Table 8 circRNAs in glioma

circBase ID (alias)	Host gene	Putative function	Upregulated/downregulated	miRNA sponge	Target gene/pathway	Reference
circ-VCAN	VCAN	–	Upregulated	–	–	[97]
circ-ZNF292	ZNF292	–	Downregulated	–	Wnt/β-catenin	[101]
hsa_circ_0000594	TTBK2	miRNA sponge	Upregulated	miR-217	HNF1β/Derlin-1	[102]
hsa_circ_0001946	CDR1	miRNA sponge	Downregulated	miR-671	–	[98]
circ-BRAF	BRAF	–	Downregulated	–	–	[106]
hsa_circ_0046701	YES1	miRNA sponge	Upregulated	miR-142	ITGB8	[99]
circ-SHKBP1	SHKBP1	miRNA sponge	Upregulated	miR-544a, miR-379	FOXP1, FOXP2	[100]
circ-FBXW7	FBXW7	Translating protein	Downregulated	–	–	[103]
hsa_circ_0001445	SMARCA5	RNA-binding proteins	Downregulated	–	SRSF1	[104]
circ-SHPRH	SHPRH	Translating protein	Downregulated	–	–	[105]

ISSN: 1756-8722