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Fig. 3 | Journal of Hematology & Oncology

Fig. 3

From: Overexpression of CLC-3 is regulated by XRCC5 and is a poor prognostic biomarker for gastric cancer

Fig. 3

The expression and function of CLC-3 were inhibited after XRCC5 knockdown. a, b The expression of CLC-3 was inhibited after XRCC5 knockdown in SGC-7901 and BGC-823 cells, and the inhibition effect was rescued by CLC-3 overexpression. c–f The proliferation and clonogenicity of SGC-7901 and BGC-823 cells were attenuated after XRCC5 knockdown, and the attenuation effects were rescued by CLC-3 overexpression (n = 3). g, h The migration and invasion of SGC-7901 and BGC-823 cells were inhibited after XRCC5 knockdown, and the inhibition effects were similarly rescued by CLC-3 overexpression (n = 3). *P < 0.05, **P < 0.01

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