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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: Overexpression of CLC-3 is regulated by XRCC5 and is a poor prognostic biomarker for gastric cancer

Fig. 4

The expression and function of CLC-3 were promoted after XRCC5 overexpression. a, b The expression of CLC-3 in SGC-7901 and BGC-823 cells was increased after XRCC5 overexpression, and the increase effects could be reversed by the CLC-3 knockdown. c–f The proliferation and clonogenicity of SGC-7901 and BGC-823 cells were promoted after XRCC5 overexpression, and these promotion effects were reversed by CLC-3 knockdown (n = 3). g, h The migration and invasion of SGC-7901 and BGC-823 cells were enhanced by XRCC5 overexpression, and the enhancement effects were similarly reversed by CLC-3 knockdown (n = 3). *P < 0.05, **P < 0.01

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