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Table 1 Correlations between CLC-3 expression and clinicopathological characteristics of GC patients

From: Overexpression of CLC-3 is regulated by XRCC5 and is a poor prognostic biomarker for gastric cancer

Variables

N

CLC-3

χ 2

P value

Low

expression

High

expression

Age

 ≤ 70

55

29

26

0.014

0.904

 > 70

35

18

17

Gender

 Male

70

35

35

0.623

0.430

 Female

20

12

8

Pathological grade

 I/II

24

15

9

1.386

0.239

 III/IV

66

32

34

Depth of invasion

 T1/T2

11

10

1

7.517

0.006

 T3/T4

79

37

42

Lymph node metastases

 N0

23

17

6

5.826

0.016

 N1/N2/N3

67

30

37

Distant metastasis

 M0

86

45

41

0.009

0.927

 M1

4

2

2

TNM stage

 I/II

37

25

12

5.930

0.015

 III/IV

53

22

31

  1. CLC-3 chloride channel-3, GC gastric cancer