Fig. 4
From: Role of platelets and platelet receptors in cancer metastasis
Role of the FcγRIIa αIIbβIII interaction on tumor cell mediated platelet activation. Prostate cancer cells induce platelet activation exploiting a FcγRIIa and Syk dependent mechanism. Obviously, platelet activation is expedited by a cross-talk between FcγRIIa and integrin αIIbβIII culminating in platelet aggregation and ADP secretion