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Table 1 Baseline characteristics of the patients whose samples were analyzed by RNAseq (n = 55)

From: Molecular profiling of hormone receptor-positive, HER2-negative breast cancers from patients treated with neoadjuvant endocrine therapy in the CARMINA 02 trial (UCBG-0609)

 

Number of samples (%)

Anastrozole therapy (Arm A)

26 (47.3)

Fulvestrant therapy (Arm B)

29 (52.7)

Age, mean (range), years

72.1 (51–88)

Age

 ≤ 70 years

21 (38.2)

 > 70 years

32 (61.8)

ECOG PS

 0

45 (81.8)

 1

10 (18.2)

Hormone replacement therapy

 Yes

18 (32.7)

 No

37 (67.2)

Tumor staging

 T2

45 (81.8)

 T3

7 (12.7)

 T4

3 (5.5)

Node staging

 N0

35 (63.6)

 N1

17 (30.9)

 N2

2 (3.6)

 N3

1 (1.7)

Elston-Ellis grade

 I

11 (20.0)

 II

38 (69.1)

 III

6 (10.9)

Histological type

 Ductal

37 (67.3)

 Lobular

15 (27.3)

 Other

3 (5.4)

Allred score: ER

 5

1 (1.8)

 6

3 (5.5)

 7

7 (12.7)

 8

44 (80.0)

Allred score: PR

 0–5

21 (38.2)

 6

11 (20.0)

 7

11 (20.0)

 8

12 (21.8)

Ki-67

 ≥ 20%

14 (25.5)

 < 20%

39 (70.9)

 ND

2 (3.6)

  1. ECOG Eastern Cooperative Oncology Group, ER estrogen receptor, ND not determined, PR progesterone receptor, PS performance status