Table 2 Genes differentially expressed between non-responders and responders in pretreatment samples
Gene symbol | Description | log2 FC (R/NR) |
|---|---|---|
Upregulated genes | ||
CHGB | Chromogranin B | 1.3 |
TPTE | Transmembrane phosphatase with tensin homology | 1.2 |
NMBR | Neuromedin-B-preferring bombesin receptor | 1.0 |
MYO3B | Myosin IIIB | 1.1 |
CEP72 | Centrosomal protein 72 | 0.9 |
GRB14 | Growth factor receptor bound protein 14 | 1.0 |
MEGF10 | Multiple epidermal growth factor-like domains protein 10 | 1.0 |
RP5-1043L13,1 | LncRNA | 1.0 |
ZXDC | ZXD family zinc finger C | 0.3 |
VSX1 | Visual system homeobox 1 | 0.9 |
MBTPS1 | Membrane bound transcription factor peptidase, site 1 | 0.6 |
CTRL | Chymotrypsin Like | 0.4 |
SESN3 | Sestrin 3 | 0.9 |
PSKH1 | Protein serine kinase H1 | 0.4 |
TPPP | Tubulin polymerization promoting protein | 1.0 |
LINC00578 | Long intergenic non-protein coding RNA 578 | 1.0 |
RP11-712B9,2 | LncRNA | 0.9 |
GBA3 | Glucosylceramidase beta 3 | 0.9 |
CPLX2 | Complexin 2 | 0.7 |
HSDL1 | Hydroxysteroid dehydrogenase like 1 | 0.5 |
AC008174,3 | LncRNA | 0.9 |
FUK | Fucokinase | 0.5 |
MT1L | Metallothionein 1L | 0.9 |
Downregulated genes | ||
ASAH1 | N-Acylsphingosine amidohydrolase 1 | − 0.8 |
ANK1 | Ankyrin 1 | − 1.0 |
PCSK1 | Proprotein convertase subtilisin/kexin type 1 | − 0.9 |
SEZ6L | Seizure related 6 homolog like | − 0.9 |
TMC3 | Transmembrane channel like 3 | − 0.9 |
RP11-761I4,3 | LncRNA | − 1.0 |
KCNK3 | Potassium two pore domain channel subfamily K member 3 | − 0.9 |