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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the β-catenin/SIRT3 signaling pathway in cervical cancer

Fig. 1

PIK3CA E542K, E545K mutation and its correlation with 18F-FDG PET/CT SUVmax. a The mutation occurrence of PIK3CA E542, E545, and H1047 in cervical cancer, breast cancer, and endometrial carcinoma. b cDNA sequence of wild-type PIK3CA and mutated at E542K and E545K. c The representative 18F-FDG PET/CT imaging in patients with wild-type and mutant PIK3CA. d Statistical analysis of SUVmax in groups with wild-type and mutant PIK3CA (n = 52; P = 0.037)

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