Fig. 7

MSCs-exo regulated the differentiation of T cells from patients with active cGVHD. a, b PBMCs were isolated from patients with active cGVHD, stimulated by T-activator CD3/CD28, and treated with PBS, Fib-exo, or MSCs-exo for 5 days. Consistently, there was a clear reduction of Th17 cells (a) in MSCs-exo-treated cells, whereas the percentage of Treg cells was increased (b). Data are expressed as the mean ± SEM. **P < .01 and ***P < .001; ns not significant