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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma

Fig. 1

Efficacy assessments of LCAR-B38M. a Individual patient response and duration of follow-up for patients who achieved at least a PR (n = 50). b One patient manifested extramedullary myeloma and wide subcutaneous metastasis. Examination on day 1, day 19, and day 84 after LCAR-B38M CAR T cell infusion showed regression of the subcutaneous metastases. c CT scans of a patient with an extramedullary lesion beside the thoracic vertebrae and severe pleural effusion at baseline and at week 3 and week 8 following LCAR-B38M CAR T cell infusion. It should be noted that the patient received thoracentesis intermittently before the CAR T treatment but did not receive thoracentesis or intrathoracic injection of drugs after treatment

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