|
AE, n (%)
|
All grade
|
Grades 1–2
|
Grade ≥ 3
|
|---|
|
Pyrexia
|
52 (91)
|
41 (72)
|
11 (19)
|
|
Cytokine release syndromea
|
51 (90)
|
47 (83)
|
4 (7)
|
|
Thrombocytopenia
|
28 (49)
|
15 (26)
|
13 (23)
|
|
Leukopenia
|
27 (47)
|
10 (18)
|
17 (30)
|
|
AST increased
|
22 (39)
|
10 (18)
|
12 (21)
|
|
Anemia
|
17 (30)
|
7 (12)
|
10 (18)
|
|
Hypotension
|
12 (21)
|
9 (16)
|
3 (5)
|
|
ALT increased
|
10 (18)
|
10 (18)
|
0
|
|
Cough
|
10 (18)
|
10 (18)
|
0
|
|
Disseminated intravascular coagulation
|
10 (18)
|
9 (16)
|
1 (2)
|
|
Hypocalcemia
|
9 (16)
|
7 (12)
|
2 (4)
|
|
Hyponatremia
|
8 (14)
|
5 (9)
|
3 (5)
|
|
Dyspnea
|
6 (11)
|
6 (11)
|
0
|
|
Nausea
|
6 (11)
|
6 (11)
|
0
|
- ALT alanine aminotransferase, AST aspartate aminotransferase
- aCytokine release syndrome assessed using modified criteria by Lee et al. [25]
