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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: Multiple myeloma-derived exosomes are enriched of amphiregulin (AREG) and activate the epidermal growth factor pathway in the bone microenvironment leading to osteoclastogenesis

Fig. 1

a Box plot represents the median level of AREG expression of 11 monoclonal gammopathy of undetermined significance (MGUS), 133 MM patients at diagnosis, and 9 plasma cell leukemia (PCL) (GSE16122). b Representative AFM image of MM1.S exosomes. c Total proteins were extracted from MM1.S cells, MM1.S exosomes (exo), and exosome-deprived conditioned medium (cm-exo) and were subjected to western blot analysis with an antibody against AREG

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