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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: lncRNA SNHG6 regulates EZH2 expression by sponging miR-26a/b and miR-214 in colorectal cancer

Fig. 4

SNHG6 affects CRC cell migration and invasion in vitro. a GSEA results were plotted to visualize the correlation between the expression of SNHG6 and genes related to cancer metastasis (ALONSO_METASTASIS). b Transwell assays were used to determine the invasion and migration abilities of SNHG6 siRNAs transfected cells. c Representative images of wound healing assays performed using HCT-6 cells and HCT-8 cells after SNHG6 silenced. d The metastasis-related proteins E-cadherin, vimentin, and MMP9 were detected by western blotting after SNHG6 knockdown. e The E-cadherin and vimentin protein levels were detected by immunofluorescence after SNHG6 knockdown. Scale bar = 50 μm. **P < 0.01 and ***P < 0.001

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