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Table 5 The list of significantly correlated DNA methylation and the expression of the promoter methylated lncRNAs (n = 23) from BCP-ALL subtypes

From: Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia

DM lncRNAs

Pearson correlation coefficient

P value

Methylation

Absolute fold change

Subtypes

AC003075.4

− 0.31

0.004

1.43

− 1.26

DUX4

AC099754.1

− 0.32

0.002

− 1.74

3.2

AC104655.3

− 0.26

0.017

− 2.27

2.07

CACNA1C-AS1

− 0.45

2.03E−05

1.97

− 1.62

CTB-25B13.9

− 0.26

0.016

− 1.73

1.46

IGF2-AS

− 0.24

0.028

− 1.33

4.95

LINC01006

− 0.39

0.001

− 2.06

2.53

PVT1

− 0.40

0.001

− 2.13

1.15

RGMB-AS1

− 0.26

0.0193

− 1.48

5.96

RP11-125B21.2

− 0.35

0.001

− 1.75

4.11

RP11-138M12.1

− 0.70

5.21E−13

− 5.98

3.77

RP11-367G6.3

− 0.30

0.004

1.98

− 1.63

RP11-624M8.1

− 0.50

1.34E−06

− 3.34

4.13

RP11-789C17.3

− 0.36

0.001

− 2.27

3.2

SERTAD4-AS1

− 0.25

0.0232

− 1.98

1.79

LINC01006

− 0.38

0.0003

1.44

− 1.56

Ph-like

RP11-138M12.1

− 0.70

5.21E−13

2.06

− 1.44

RP11-305F18.1

− 0.64

5.36E−11

1.76

− 2.08

AC099754.1

− 0.33

0.002

1.21

− 1.36

ACVR2B-AS1

− 0.36

0.0009

2.18

− 1.75

LINC00996

− 0.39

0.0003

− 1.56

2.11

ERICH1-AS1

− 0.40

0.0006

− 1.82

2.21

DIO3OS

− 0.31

0.0037

− 1.76

4.05

NH-HeH

U3

− 0.83

1.346E-22

− 2.01

2.43

  1. The lncRNAs are promoter differentially methylated and differentially expressed in their corresponding subtypes. DM, differentially methylated. The significance is calculated based on Pearson correlation rate and two-tailed P value ≤ 0.05