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Table 5 The list of significantly correlated DNA methylation and the expression of the promoter methylated lncRNAs (n = 23) from BCP-ALL subtypes

From: Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia

DM lncRNAs Pearson correlation coefficient P value Methylation Absolute fold change Subtypes
AC003075.4 − 0.31 0.004 1.43 − 1.26 DUX4
AC099754.1 − 0.32 0.002 − 1.74 3.2
AC104655.3 − 0.26 0.017 − 2.27 2.07
CACNA1C-AS1 − 0.45 2.03E−05 1.97 − 1.62
CTB-25B13.9 − 0.26 0.016 − 1.73 1.46
IGF2-AS − 0.24 0.028 − 1.33 4.95
LINC01006 − 0.39 0.001 − 2.06 2.53
PVT1 − 0.40 0.001 − 2.13 1.15
RGMB-AS1 − 0.26 0.0193 − 1.48 5.96
RP11-125B21.2 − 0.35 0.001 − 1.75 4.11
RP11-138M12.1 − 0.70 5.21E−13 − 5.98 3.77
RP11-367G6.3 − 0.30 0.004 1.98 − 1.63
RP11-624M8.1 − 0.50 1.34E−06 − 3.34 4.13
RP11-789C17.3 − 0.36 0.001 − 2.27 3.2
SERTAD4-AS1 − 0.25 0.0232 − 1.98 1.79
LINC01006 − 0.38 0.0003 1.44 − 1.56 Ph-like
RP11-138M12.1 − 0.70 5.21E−13 2.06 − 1.44
RP11-305F18.1 − 0.64 5.36E−11 1.76 − 2.08
AC099754.1 − 0.33 0.002 1.21 − 1.36
ACVR2B-AS1 − 0.36 0.0009 2.18 − 1.75
LINC00996 − 0.39 0.0003 − 1.56 2.11
ERICH1-AS1 − 0.40 0.0006 − 1.82 2.21
DIO3OS − 0.31 0.0037 − 1.76 4.05 NH-HeH
U3 − 0.83 1.346E-22 − 2.01 2.43
  1. The lncRNAs are promoter differentially methylated and differentially expressed in their corresponding subtypes. DM, differentially methylated. The significance is calculated based on Pearson correlation rate and two-tailed P value ≤ 0.05