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Table 1 The IC50 value of adriamycin in different cells

From: Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible for maintaining the stemness of breast cancer cells

Cell name IC50 value ((μM) P value
MCF-7 3.637 ± 0.028  
MCF-7-Z1-UTR 6.496 ± 0.017 **
MCF-7-Z2P-UTR 6.49 ± 0.013 **
MCF-7-six2 9.31 ± 0.009 **
MCF-7-Plko-Z1 0.4349 ± 0.024 **
MCF-7-Plko-Z2P 0.546 ± 0.029 **
MCF-7-Plko-six2 0.4871 ± 0.017 **
MDA-MB-231 2.853 ± 0.034  
231-Z1-UTR 4.208 ± 0.015 **
231-Z2P-UTR 4.081 ± 0.011 **
231-Plko-Z1 0.6296 ± 0.033 **
231-Plko-Z2P 0.7747 ± 0.036 **
231-Plko-six2 0.3066 ± 0.030 **
MCF-7-Adr 41.12 ± 5.93  
MCF-7-Adr-Plko-Z1 19.87 ± 3.33 **
MCF-7-Adr-Plko-Z2P 11.33 ± 1.68 **
MCF-7-Adr-Plko-six2 6.971 ± 1.10 **
MCF-7-Adr-Plko-six2-Z1-UTR 10.8 ± 1.31 ##
MCF-7-Adr-Plko-six2-Z2P-UTR 9.235 ± 1.12 ##
  1. **p < 0.01 vs MCF-7 or MDA-MB-231 or MCF-7-Adr cells, ##p < 0.01 vs MCF-7-Plko-six2 cells