TY - JOUR AU - Hwang, Wei-Lun AU - Lan, Hsin-Yi AU - Cheng, Wei-Chung AU - Huang, Shih-Ching AU - Yang, Muh-Hwa PY - 2019 DA - 2019/01/25 TI - Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer JO - Journal of Hematology & Oncology SP - 10 VL - 12 IS - 1 AB - Cell-cell interactions maintain tissue homeostasis and contribute to dynamic alteration of the tumor microenvironment (TME). Communication between cancer and host cells not only promotes advanced disease aggression but also determines therapeutic response in cancer patients. Despite accumulating evidence supporting the role of tumor-infiltrating immunocytes in modulating tumor immunity, the interplay between heterogeneous tumor subpopulations and immunocytes is elusive. SN - 1756-8722 UR - https://doi.org/10.1186/s13045-019-0699-4 DO - 10.1186/s13045-019-0699-4 ID - Hwang2019 ER -