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Table 1 Correlation of SPAG5 expression and clinical features of TNBC patients

From: SPAG5 upregulation contributes to enhanced c-MYC transcriptional activity via interaction with c-MYC binding protein in triple-negative breast cancer

Variable

Overall (N = 42)

SPAG5

Low expression (N = 20)

High expression (N = 22)

 

N

%

N

%

N

%

P

Age, years

0.746

  ≤ 50

20

47.62

9

45.00

11

50.00

 

  > 50

22

52.38

11

55.00

11

50.00

Tumor size, cm

0.72

  < 2

21

50.00

9

45.00

12

54.55

 

  2 ≤ T < 5

18

42.86

9

45.00

9

40.91

  ≥ 5

3

7.14

2

10.00

1

4.55

Histological grade

0.98

  I/II

23

54.76

11

55.00

12

54.55

 

  III

19

45.24

9

45.00

10

45.45

Node status

0.04

 pN0 (none)

22

52.38

12

60.00

10

45.45

 

 pN1 (1–3)

8

19.05

3

15.00

5

22.73

 pN2 (4–9)

4

9.52

4

20.00

0

0.00

 pN3 (≥ 10)

7

16.67

1

5.00

6

27.27

 pNX

1

2.38

0

0.00

1

4.55

Local recurrence

0.009

  Absence

35

83.33

20

100.00

15

68.18

 

  Presence

7

16.67

0

0.00

7

31.82

Distant metastasis

0.243

  Absence

34

80.95

18

90.00

16

72.73

 

  Presence

8

19.05

2

10.00

6

27.27