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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: Expert consensus on multidisciplinary therapy of colorectal cancer with lung metastases (2019 edition)

Fig. 1

Principles of treatment for lung metastases. Note 1: Number sign is patients with primary tumor or local recurrence. If the primary tumor or local recurrence that cannot be radically treated initially, reassess the possibility of radical treatment after (intensive) systemic therapy: (1) if the lesion has converted to a curable tumor, then the above process can be used as a reference; (2) if the tumor is still incurable, a comprehensive therapy protocol should be formulated after multidisciplinary discussion (in such cases, the lesion could be managed as “an incurable metastatic lesion”). Note 2: For lung metastases + extrapulmonary metastases at any site other than the liver, please refer to the treatment principles for “lung metastases + liver metastases.” Note 3: Non-initial lung metastases are a highly heterogenous group of diseases. In contrast to initial lung metastases, these patients have previously received drug treatment, and further drug efficacy is relatively low. For these patients, it is recommended that a final decision be made after the MDT team has comprehensively examined the patient’s physical status, efficacy and adverse events from previous treatment, drug discontinuation duration, and the biological behavior of tumors

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