Skip to main content

Table 2 The UCART19 cell doses in the universal CAR T trials PALL and CALM

From: Clinical trials of dual-target CAR T cells, donor-derived CAR T cells, and universal CAR T cells for acute lymphoid leukemia

PALL dose

CALM dose levels

weight-based dose (1.1 to 2.3 × 106 cells/kg)

DL1:6 × 106

≈ 1 × 105 cells/kg

DL2:6 or 8 × 107

≈ 1 × 106 cells/kg

DL3:1.8 or 2.4 × 108

≈ 3 × 106 cells/kg

  1. The cell doses were based on data presented at 2018 ASH Annual meeting by Benjamin et al. [115]
  2. DL dose level; PALL UCART19 trial in pediatric patients, NCT 02808442; CALM UCART19 trial in adult patients, NCT 02746952
Back to article page

Journal of Hematology & Oncology

ISSN: 1756-8722

Contact us