Fig. 4

LincK promoted proliferation of breast cancer cells in vitro. a, c, e MTS assay in MCF-7 (a), MDA-MB-453 (c), and MDA-MB-231 (e) cells with LincK knockdown or overexpression. Representative results of triplicate experiments. Data were shown as means ± S.D. (*p < 0.05; **p < 0.01 by Student’s t test). b, d, f BrdU incorporation assay in MCF-7 (b), MDA-MB-453 (d), and MDA-MB-231 (f) with LincK knockdown or overexpression. Data were shown as means ± S.D. (n = 3, *p < 0.05; **p < 0.01 by Student’s t test). g, h, i Clone formation assay in MCF-7 (g), MDA-MB-453 (h), and MDA-MB-231 (i) with LincK knockdown or overexpression. Data showed mean ± S.D. of three independent experiments. (*p < 0.05; **p < 0.01 by Student’s t test)