Fig. 4
From: Platelet integrin αIIbβ3: signal transduction, regulation, and its therapeutic targeting
Amino acid sequence of the C-terminal tail of integrin β3, highlighting interaction sites involved in integrin αIIbβ3 bidirectional signaling. Calpain cleavage sites are indicated by arrows. Phosphorylatable amino acid residues (tyrosine and threonine) are labeled in red. Positions of the horizontal lines indicate sites on the integrin β3 cytoplasmic tail that interact with cytoplasmic signaling proteins