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Table 1 Correlations between RNF128 and clinicopathological features in 196 melanoma patients

From: Downregulation of RNF128 activates Wnt/β-catenin signaling to induce cellular EMT and stemness via CD44 and CTTN ubiquitination in melanoma

Variable

Number of patients

p value*

RNF128Low

RNF128High

Age, years

  < 60

34

44

0.220

  ≥ 60

62

56

 

Gender

 Male

49

55

0.579

 Female

47

45

 

Anatomic site

 Acra

56

45

0.155

 Trunk

19

29

 

 Other

21

26

 

Histologic type

 Superficial spreading

26

20

0.274

 Nodular

15

26

 

 Acral

36

33

 

 Lentigo maligna

19

21

 

Ulceration

 Present

15

11

0.340

 Absent

81

89

 

Breslow depth (mm)

  ≤ 2

47

65

0.023

  > 2

49

35

 

Clark level

 I–III

45

61

0.047

 IV–V

51

39

 

Lymph nodes metastasis

 No

66

75

0.330

 Yes

30

25

 

Distant metastasis

 No

64

83

0.008

 Yes

32

17

 

Clinical stage

 I–II

50

73

0.002

 III–IV

46

27

 
  1. Note: A chi-square test was used for comparing groups between low and high RNF128 expression. *p < 0.05 was considered significant
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Journal of Hematology & Oncology

ISSN: 1756-8722

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