Fig. 1

Molecular subgroups of medulloblastoma. The current consensus divides medulloblastoma into four subgroups: WNT-activated (WNT), SHH-activated (SHH), group 3, and group 4. Only the most frequently altered genes are listed for group 3 and group 4 (a). Adult samples are extremely rare among group 3 patients, while the majority of group 4 tumors consist of children (b)