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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Emerging therapies for non-small cell lung cancer

Fig. 2

Chord diagrams for sensitive and resistant mutations regarding ALK-TKIs. Both preclinical data and clinical reported cases (preferred) were enrolled to determine the efficacy of ALK-TKIs to different ALK-dependent mutations. Crizotinib had smallest sensitive mutation profiles compared to lorlatinib while opposite in resistant profiles. a Mutation profiles showed responsiveness to different ALK-TKIs. b Mutation profiles reported to be resistant to different ALK-TKIs

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