TY - JOUR AU - Quail, D. F. AU - Joyce, J. A. PY - 2013 DA - 2013// TI - Microenvironmental regulation of tumour progression and metastasis JO - Nat Med VL - 19 UR - https://doi.org/10.1038/nm.3394 DO - 10.1038/nm.3394 ID - Quail2013 ER - TY - JOUR AU - Junttila, M. R. AU - Sauvage, F. J. D. PY - 2013 DA - 2013// TI - Influence of tumour micro-environment heterogeneity on therapeutic response JO - Nature. VL - 501 UR - https://doi.org/10.1038/nature12626 DO - 10.1038/nature12626 ID - Junttila2013 ER - TY - JOUR AU - Farazi, P. A. AU - Depinho, R. A. PY - 2006 DA - 2006// TI - Hepatocellular carcinoma pathogenesis: from genes to environment JO - Nat Rev Cancer. VL - 6 UR - https://doi.org/10.1038/nrc1934 DO - 10.1038/nrc1934 ID - Farazi2006 ER - TY - JOUR AU - Bissell, M. J. AU - Hines, W. C. PY - 2011 DA - 2011// TI - Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression JO - Nat Med VL - 17 UR - https://doi.org/10.1038/nm.2328 DO - 10.1038/nm.2328 ID - Bissell2011 ER - TY - JOUR AU - Becker, A. AU - Thakur, B. K. AU - Weiss, J. M. AU - Kim, H. S. AU - Peinado, H. AU - Lyden, D. PY - 2016 DA - 2016// TI - Extracellular vesicles in cancer: cell-to-cell mediators of metastasis JO - Cancer Cell. VL - 30 UR - https://doi.org/10.1016/j.ccell.2016.10.009 DO - 10.1016/j.ccell.2016.10.009 ID - Becker2016 ER - TY - JOUR AU - Kalluri, R. PY - 2016 DA - 2016// TI - The biology and function of exosomes in cancer JO - J Clin Invest VL - 126 UR - https://doi.org/10.1172/JCI81135 DO - 10.1172/JCI81135 ID - Kalluri2016 ER - TY - JOUR AU - Pan, B. T. AU - Johnstone, R. M. PY - 1983 DA - 1983// TI - Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: selective externalization of the receptor JO - Cell. VL - 33 UR - https://doi.org/10.1016/0092-8674(83)90040-5 DO - 10.1016/0092-8674(83)90040-5 ID - Pan1983 ER - TY - JOUR AU - Cocucci, E. AU - Meldolesi, J. PY - 2015 DA - 2015// TI - Ectosomes and exosomes: shedding the confusion between extracellular vesicles JO - Trends Cell Biol VL - 25 UR - https://doi.org/10.1016/j.tcb.2015.01.004 DO - 10.1016/j.tcb.2015.01.004 ID - Cocucci2015 ER - TY - JOUR AU - Pfeffer, S. R. PY - 2007 DA - 2007// TI - Unsolved mysteries in membrane traffic JO - Annu Rev of Biochem VL - 76 UR - https://doi.org/10.1146/annurev.biochem.76.061705.130002 DO - 10.1146/annurev.biochem.76.061705.130002 ID - Pfeffer2007 ER - TY - JOUR AU - Kosaka, N. PY - 2016 DA - 2016// TI - Decoding the secret of cancer by means of extracellular vesicles JO - J Clin Med VL - 5 UR - https://doi.org/10.3390/jcm5020022 DO - 10.3390/jcm5020022 ID - Kosaka2016 ER - TY - JOUR AU - Record, M. i. c. h. e. l. AU - Carayon, K. e. v. i. n. AU - Poirot, M. a. r. c. AU - Silvente-Poirot, S. a. n. d. r. i. n. e. PY - 2014 DA - 2014// TI - Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies JO - Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids VL - 1841 UR - https://doi.org/10.1016/j.bbalip.2013.10.004 DO - 10.1016/j.bbalip.2013.10.004 ID - Record2014 ER - TY - JOUR AU - Takayuki, K. AU - Wen-Lang, L. AU - Yan, I. K. AU - Chiara, B. AU - Tushar, P. PY - 2011 DA - 2011// TI - Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth JO - Hepatology. VL - 54 ID - Takayuki2011 ER - TY - JOUR AU - Oosthuyzen, W. AU - Sime, N. E. L. AU - Ivy, J. R. AU - Turtle, E. J. AU - Street, J. M. AU - Pound, J. PY - 2014 DA - 2014// TI - Quantification of human urinary exosomes by nanoparticle tracking analysis JO - J Phys VL - 229 ID - Oosthuyzen2014 ER - TY - JOUR AU - Street, J. o. n. a. t. h. a. n. M. AU - Barran, P. e. r. d. i. t. a. E. AU - Mackay, C. L. o. g. a. n. AU - Weidt, S. t. e. f. a. n. AU - Balmforth, C. r. a. i. g. AU - Walsh, T. i. m. S. AU - Chalmers, R. o. d. T. A. AU - Webb, D. a. v. i. d. J. AU - Dear, J. a. m. e. s. W. PY - 2012 DA - 2012// TI - Identification and proteomic profiling of exosomes in human cerebrospinal fluid JO - Journal of Translational Medicine VL - 10 UR - https://doi.org/10.1186/1479-5876-10-5 DO - 10.1186/1479-5876-10-5 ID - Street2012 ER - TY - JOUR AU - Lässer, C. AU - Alikhani, V. S. AU - Ekström, K. AU - Eldh, M. AU - Paredes, P. T. AU - Bossios, A. PY - 2011 DA - 2011// TI - Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages JO - J Transl Med VL - 9 UR - https://doi.org/10.1186/1479-5876-9-9 DO - 10.1186/1479-5876-9-9 ID - Lässer2011 ER - TY - JOUR AU - Bang, C. AU - Thum, T. PY - 2012 DA - 2012// TI - Exosomes: new players in cell-cell communication JO - Int J Biochem Cell Biol. VL - 44 UR - https://doi.org/10.1016/j.biocel.2012.08.007 DO - 10.1016/j.biocel.2012.08.007 ID - Bang2012 ER - TY - JOUR AU - Sun, D. o. n. g. m. e. i. AU - Zhuang, X. i. a. o. y. i. n. g. AU - Zhang, S. h. u. a. n. g. q. i. n. AU - Deng, Z. h. o. n. g. -. B. i. n. AU - Grizzle, W. i. l. l. i. a. m. AU - Miller, D. o. n. a. l. d. AU - Zhang, H. u. a. n. g. -. G. e. PY - 2013 DA - 2013// TI - Exosomes are endogenous nanoparticles that can deliver biological information between cells JO - Advanced Drug Delivery Reviews VL - 65 UR - https://doi.org/10.1016/j.addr.2012.07.002 DO - 10.1016/j.addr.2012.07.002 ID - Sun2013 ER - TY - JOUR AU - Vlassov, A. V. AU - Magdaleno, S. AU - Setterquist, R. AU - Conrad, R. PY - 2012 DA - 2012// TI - Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials JO - Biochim Biophys Acta. VL - 1820 UR - https://doi.org/10.1016/j.bbagen.2012.03.017 DO - 10.1016/j.bbagen.2012.03.017 ID - Vlassov2012 ER - TY - JOUR AU - Azmi, A. S. AU - Bao, B. AU - Sarkar, F. H. PY - 2013 DA - 2013// TI - Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review JO - Cancer Metastasis Rev VL - 32 UR - https://doi.org/10.1007/s10555-013-9441-9 DO - 10.1007/s10555-013-9441-9 ID - Azmi2013 ER - TY - JOUR AU - Masyuk, A. I. AU - Huang, B. Q. AU - Ward, C. J. AU - Gradilone, S. A. AU - Banales, J. M. AU - Masyuk, T. V. PY - 2010 DA - 2010// TI - Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia JO - Am J Physiol Gastrointest Liver Physiol. VL - 299 UR - https://doi.org/10.1152/ajpgi.00093.2010 DO - 10.1152/ajpgi.00093.2010 ID - Masyuk2010 ER - TY - JOUR AU - Zhong-Bin, D. AU - Xiaoying, Z. AU - Songwen, J. AU - Xiaoyu, X. AU - Jingyao, M. AU - Qilong, W. PY - 2013 DA - 2013// TI - Intestinal mucus-derived nanoparticle-mediated activation of Wnt/β-catenin signaling plays a role in induction of liver natural killer T cell anergy in mice JO - Hepatology. VL - 57 UR - https://doi.org/10.1002/hep.26086 DO - 10.1002/hep.26086 ID - Zhong-Bin2013 ER - TY - STD TI - Fonsato V, Fau CF. Herrera MB, Herrera Mb Fau - Cavallari C, Cavallari C Fau - Deregibus MC, Deregibus Mc Fau - Cisterna B, Cisterna B Fau - Bruno S, et al. Human liver stem cell-derived microvesicles inhibit hepatoma growth in SCID mice by delivering antitumour microRNAs. Stem Cells. 2012:1985–98. ID - ref22 ER - TY - JOUR AU - Witek, R. P. AU - Yang, L. AU - Liu, R. AU - Jung, Y. AU - Omenetti, A. AU - Syn, W. K. PY - 2009 DA - 2009// TI - Liver cell–derived microparticles activate hedgehog signaling and alter gene expression in hepatic endothelial cells JO - Gastroenterology. VL - 136 UR - https://doi.org/10.1053/j.gastro.2008.09.066 DO - 10.1053/j.gastro.2008.09.066 ID - Witek2009 ER - TY - JOUR AU - Wakim, L. M. AU - Bevan, M. J. PY - 2011 DA - 2011// TI - Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection JO - Nature. VL - 471 UR - https://doi.org/10.1038/nature09863 DO - 10.1038/nature09863 ID - Wakim2011 ER - TY - JOUR AU - Greuter, T. AU - Shah, V. H. PY - 2016 DA - 2016// TI - Hepatic sinusoids in liver injury, inflammation, and fibrosis: new pathophysiological insights JO - J Gastroenterol VL - 51 UR - https://doi.org/10.1007/s00535-016-1190-4 DO - 10.1007/s00535-016-1190-4 ID - Greuter2016 ER - TY - JOUR AU - Royo, F. AU - Schlangen, K. AU - Palomo, L. AU - Gonzalez, E. AU - Condevancells, J. AU - Berisa, A. PY - 2013 DA - 2013// TI - Transcriptome of extracellular vesicles released by hepatocytes JO - Plos One. VL - 8 UR - https://doi.org/10.1371/journal.pone.0068693 DO - 10.1371/journal.pone.0068693 ID - Royo2013 ER - TY - JOUR AU - Hirsova, P. AU - Ibrahim, S. H. AU - Krishnan, A. AU - Verma, V. K. AU - Bronk, S. F. AU - Werneburg, N. W. PY - 2016 DA - 2016// TI - Lipid-induced signaling causes release of inflammatory extracellular vesicles from hepatocytes JO - Gastroenterology. VL - 150 UR - https://doi.org/10.1053/j.gastro.2015.12.037 DO - 10.1053/j.gastro.2015.12.037 ID - Hirsova2016 ER - TY - JOUR AU - Chahar, H. S. AU - Bao, X. AU - Casola, A. PY - 2015 DA - 2015// TI - Exosomes and their role in the life cycle and pathogenesis of RNA viruses JO - Viruses. VL - 7 UR - https://doi.org/10.3390/v7062770 DO - 10.3390/v7062770 ID - Chahar2015 ER - TY - JOUR AU - Kouwaki, T. AU - Okamoto, M. AU - Tsukamoto, H. AU - Fukushima, Y. AU - Oshiumi, H. PY - 2017 DA - 2017// TI - Extracellular vesicles deliver host and virus RNA and regulate innate immune response JO - Int J Mol Sci VL - 18 UR - https://doi.org/10.3390/ijms18030666 DO - 10.3390/ijms18030666 ID - Kouwaki2017 ER - TY - JOUR AU - Momen-Heravi, F. AU - Saha, B. AU - Kodys, K. AU - Catalano, D. AU - Satishchandran, A. AU - Szabo, G. PY - 2015 DA - 2015// TI - Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis JO - J Transl Med VL - 13 UR - https://doi.org/10.1186/s12967-015-0623-9 DO - 10.1186/s12967-015-0623-9 ID - Momen-Heravi2015 ER - TY - JOUR AU - Saha, B. AU - Momen-Heravi, F. AU - Kodys, K. AU - Szabo, G. PY - 2016 DA - 2016// TI - MicroRNA cargo of extracellular vesicles from alcohol-exposed monocytes signals naive monocytes to differentiate into M2 macrophages JO - J Biol Chem VL - 291 UR - https://doi.org/10.1074/jbc.M115.694133 DO - 10.1074/jbc.M115.694133 ID - Saha2016 ER - TY - JOUR AU - Li, C. AU - Alyssa, C. AU - Yu, Z. AU - Ruju, C. AU - Bo, Y. AU - Kitty, A. PY - 2014 DA - 2014// TI - Epigenetic regulation of connective tissue growth factor by MicroRNA-214 delivery in exosomes from mouse or human hepatic stellate cells JO - Hepatology. VL - 59 UR - https://doi.org/10.1002/hep.26768 DO - 10.1002/hep.26768 ID - Li2014 ER - TY - JOUR AU - El–Serag, H. B. AU - Rudolph, K. L. PY - 2007 DA - 2007// TI - Hepatocellular carcinoma: epidemiology and molecular carcinogenesis JO - Gastroenterology. VL - 132 UR - https://doi.org/10.1053/j.gastro.2007.04.061 DO - 10.1053/j.gastro.2007.04.061 ID - El–Serag2007 ER - TY - JOUR AU - Blum, H. E. AU - Moradpour, D. PY - 2011 DA - 2011// TI - Hepatocellular carcinoma JO - N Engl J Med VL - 365 UR - https://doi.org/10.1056/NEJMra1001683 DO - 10.1056/NEJMra1001683 ID - Blum2011 ER - TY - JOUR AU - Leonardi, G. C. AU - Candido, S. AU - Cervello, M. AU - Nicolosi, D. AU - Raiti, F. AU - Travali, S. PY - 2012 DA - 2012// TI - The tumour microenvironment in hepatocellular carcinoma (review) JO - Int J Oncol VL - 40 ID - Leonardi2012 ER - TY - JOUR AU - Feingold, M. AU - Hall, B. D. AU - Lacassie, Y. AU - Martínez-Frías, M. L. PY - 1997 DA - 1997// TI - Syndrome of microcephaly, facial and hand abnormalities, tracheoesophageal fistula, duodenal atresia, and developmental delay JO - Am J Med Genet A. VL - 69 UR - https://doi.org/3.0.CO;2-K DO - 3.0.CO;2-K ID - Feingold1997 ER - TY - JOUR AU - Hellerbrand, C. PY - 2013 DA - 2013// TI - Hepatic stellate cells—the pericytes in the liver JO - Pflügers Archiv:Eur J Physiol VL - 465 UR - https://doi.org/10.1007/s00424-012-1209-5 DO - 10.1007/s00424-012-1209-5 ID - Hellerbrand2013 ER - TY - JOUR AU - Amann, T. AU - Bataille, F. AU - Spruss, T. AU - Mühlbauer, M. AU - Gäbele, E. AU - Schölmerich, J. PY - 2010 DA - 2010// TI - Activated hepatic stellate cells promote tumourigenicity of hepatocellular carcinoma JO - Cancer Sci VL - 100 UR - https://doi.org/10.1111/j.1349-7006.2009.01087.x DO - 10.1111/j.1349-7006.2009.01087.x ID - Amann2010 ER - TY - JOUR AU - Xiong, S. AU - Wang, R. AU - Chen, Q. AU - Luo, J. AU - Wang, J. AU - Zhao, Z. PY - 2018 DA - 2018// TI - Cancer-associated fibroblasts promote stem cell-like properties of hepatocellular carcinoma cells through IL-6/STAT3/Notch signaling JO - Am J Cancer Res. VL - 8 ID - Xiong2018 ER - TY - JOUR AU - Park, S. Y. AU - Jeong, K. J. AU - Panupinthu, N. AU - Yu, S. AU - Lee, J. AU - Han, J. W. PY - 2011 DA - 2011// TI - Lysophosphatidic acid augments human hepatocellular carcinoma cell invasion through LPA1 receptor and MMP-9 expression JO - Oncogene. VL - 30 UR - https://doi.org/10.1038/onc.2010.517 DO - 10.1038/onc.2010.517 ID - Park2011 ER - TY - JOUR AU - Gajewski, T. h. o. m. a. s. F. AU - Schreiber, H. a. n. s. AU - Fu, Y. a. n. g. -. X. i. n. PY - 2013 DA - 2013// TI - Innate and adaptive immune cells in the tumor microenvironment JO - Nature Immunology VL - 14 UR - https://doi.org/10.1038/ni.2703 DO - 10.1038/ni.2703 ID - Gajewski2013 ER - TY - JOUR AU - Zamarron, B. F. AU - Chen, W. PY - 2011 DA - 2011// TI - Dual roles of immune cells and their factors in cancer development and progression JO - Int J Biol Sci. VL - 7 UR - https://doi.org/10.7150/ijbs.7.651 DO - 10.7150/ijbs.7.651 ID - Zamarron2011 ER - TY - JOUR AU - Zhang, S. AU - Sun, W. Y. AU - Wu, J. J. AU - Wei, W. PY - 2014 DA - 2014// TI - TGF-beta signaling pathway as a pharmacological target in liver diseases JO - Pharmacol Res. VL - 85 UR - https://doi.org/10.1016/j.phrs.2014.05.005 DO - 10.1016/j.phrs.2014.05.005 ID - Zhang2014 ER - TY - JOUR AU - Postic, C. AU - Dentin, R. AU - Girard, J. PY - 2004 DA - 2004// TI - Role of the liver in the control of carbohydrate and lipid homeostasis JO - Diabetes Metab. VL - 30 UR - https://doi.org/10.1016/S1262-3636(07)70133-7 DO - 10.1016/S1262-3636(07)70133-7 ID - Postic2004 ER - TY - JOUR AU - Lippolis, C. AU - Refolo, M. G. AU - D'Alessandro, R. AU - Carella, N. AU - Messa, C. AU - Cavallini, A. PY - 2015 DA - 2015// TI - Resistance to multikinase inhibitor actions mediated by insulin like growth factor-1 JO - J Exp Clin Cancer Res. VL - 34 UR - https://doi.org/10.1186/s13046-015-0210-1 DO - 10.1186/s13046-015-0210-1 ID - Lippolis2015 ER - TY - JOUR AU - Streuli, C. H. AU - Akhtar, N. PY - 2009 DA - 2009// TI - Signal co-operation between integrins and other receptor systems JO - Biochem J. VL - 418 UR - https://doi.org/10.1042/BJ20081948 DO - 10.1042/BJ20081948 ID - Streuli2009 ER - TY - JOUR AU - Hanahan, D. AU - Coussens, L. PY - 2012 DA - 2012// TI - Accessories to the crime: functions of cells recruited to the tumour microenvironment JO - Cancer Cell. VL - 21 UR - https://doi.org/10.1016/j.ccr.2012.02.022 DO - 10.1016/j.ccr.2012.02.022 ID - Hanahan2012 ER - TY - JOUR AU - Pengfei, L. AU - Weaver, V. M. AU - Zena, W. PY - 2012 DA - 2012// TI - The extracellular matrix: a dynamic niche in cancer progression JO - J Cell Biol VL - 196 UR - https://doi.org/10.1083/jcb.201102147 DO - 10.1083/jcb.201102147 ID - Pengfei2012 ER - TY - JOUR AU - Chen, J. AU - Wang, Q. AU - Xh, H. X. AU - Chen, X. AU - Cao, L. AU - Chen, L. PY - 2010 DA - 2010// TI - Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: association with MMP-9 JO - Hepatol Res VL - 39 UR - https://doi.org/10.1111/j.1872-034X.2008.00449.x DO - 10.1111/j.1872-034X.2008.00449.x ID - Chen2010 ER - TY - JOUR AU - Fang, T. AU - Lv, H. AU - Lv, G. AU - Li, T. AU - Wang, C. AU - Han, Q. PY - 2018 DA - 2018// TI - Tumour-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer JO - Nat Commun VL - 9 UR - https://doi.org/10.1038/s41467-017-02583-0 DO - 10.1038/s41467-017-02583-0 ID - Fang2018 ER - TY - JOUR AU - María, M. AU - Cristina, G. V. AU - Carolina, V. B. AU - Susana, G. AU - Fátima, S. C. AU - Ángel, G. M. PY - 2011 DA - 2011// TI - Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells JO - Nat Commun VL - 2 UR - https://doi.org/10.1038/ncomms1285 DO - 10.1038/ncomms1285 ID - María2011 ER - TY - JOUR AU - Moris, D. AU - Lu, L. AU - Qian, S. PY - 2017 DA - 2017// TI - Mechanisms of liver-induced tolerance JO - Curr Opin Organ Transplant. VL - 22 ID - Moris2017 ER - TY - JOUR AU - Yang, N. AU - Li, S. AU - Li, G. AU - Zhang, S. AU - Tang, X. AU - Ni, S. PY - 2016 DA - 2016// TI - The role of extracellular vesicles in mediating progression, metastasis and potential treatment of hepatocellular carcinoma JO - Oncotarget. VL - 8 ID - Yang2016 ER - TY - JOUR AU - Pardee, A. D. AU - Butterfield, L. H. PY - 2012 DA - 2012// TI - Immunotherapy of hepatocellular carcinoma: unique challenges and clinical opportunities JO - Oncoimmunology. VL - 1 UR - https://doi.org/10.4161/onci.1.1.18344 DO - 10.4161/onci.1.1.18344 ID - Pardee2012 ER - TY - STD TI - Wang X, Shen H, Zhangyuan G, Huang R, Zhang W, He Q, et al. 14-3-3zeta delivered by hepatocellular carcinoma-derived exosomes impaired anti-tumour function of tumour-infiltrating T lymphocytes. Cell Death Dis. 2018:159. ID - ref55 ER - TY - JOUR AU - Smyth, M. J. AU - Jeremy, S. AU - Erika, C. AU - Nadeen, Z. AU - Yokoyama, W. M. AU - Yoshihiro, H. PY - 2005 DA - 2005// TI - NKG2D function protects the host from tumour initiation JO - J Exp Med VL - 202 UR - https://doi.org/10.1084/jem.20050994 DO - 10.1084/jem.20050994 ID - Smyth2005 ER - TY - JOUR AU - Nadia, G. AU - Xim, T. Y. AU - Joncker, N. T. AU - Augustine, C. AU - Fermin, G. AU - Na, X. PY - 2008 DA - 2008// TI - NKG2D-deficient mice are defective in tumour surveillance in models of spontaneous malignancy JO - Immunity. VL - 28 UR - https://doi.org/10.1016/j.immuni.2008.02.016 DO - 10.1016/j.immuni.2008.02.016 ID - Nadia2008 ER - TY - JOUR AU - Omodele, A. AU - Philippe, B. AU - Lola, F. M. AU - Sonia, A. G. AU - Skepper, J. N. AU - Mar, V. G. PY - 2010 DA - 2010// TI - Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumour cells in exosomes JO - Cancer Res VL - 70 UR - https://doi.org/10.1158/0008-5472.CAN-09-1688 DO - 10.1158/0008-5472.CAN-09-1688 ID - Omodele2010 ER - TY - JOUR AU - Rao, Q. AU - Zuo, B. AU - Lu, Z. AU - Gao, X. AU - You, A. AU - Wu, C. PY - 2016 DA - 2016// TI - Tumour-derived exosomes elicit tumour suppression in murine hepatocellular carcinoma models and humans in vitro JO - Hepatology. VL - 64 UR - https://doi.org/10.1002/hep.28549 DO - 10.1002/hep.28549 ID - Rao2016 ER - TY - JOUR AU - Chow, A. AU - Zhou, W. AU - Liu, L. AU - Fong, M. Y. AU - Champer, J. AU - Haute, D. PY - 2014 DA - 2014// TI - Macrophage immunomodulation by breast cancer-derived exosomes requires toll-like receptor 2-mediated activation of NF-kappaB JO - Sci Rep. VL - 4 UR - https://doi.org/10.1038/srep05750 DO - 10.1038/srep05750 ID - Chow2014 ER - TY - JOUR AU - Costa-Silva, B. AU - Aiello, N. M. AU - Ocean, A. J. AU - Singh, S. AU - Zhang, H. AU - Thakur, B. K. PY - 2015 DA - 2015// TI - Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver JO - Nat Cell Biol. VL - 17 UR - https://doi.org/10.1038/ncb3169 DO - 10.1038/ncb3169 ID - Costa-Silva2015 ER - TY - JOUR AU - Yu, L. PY - 2017 DA - 2017// TI - Exosomes from melatonin treated hepatocellularcarcinoma cells alter the immunosupression status through STAT3 pathway in macrophages JO - Int J Biol Sci VL - 13 UR - https://doi.org/10.7150/ijbs.19642 DO - 10.7150/ijbs.19642 ID - Yu2017 ER - TY - JOUR AU - Xiong, L. AU - Zhen, S. AU - Yu, Q. AU - Gong, Z. PY - 2017 DA - 2017// TI - HCV-E2 inhibits hepatocellular carcinoma metastasis by stimulating mast cells to secrete exosomal shuttle microRNAs JO - Oncol Lett. VL - 14 UR - https://doi.org/10.3892/ol.2017.6433 DO - 10.3892/ol.2017.6433 ID - Xiong2017 ER - TY - JOUR AU - Aucher, A. AU - Rudnicka, D. AU - Davis, D. M. PY - 2013 DA - 2013// TI - MicroRNAs transfer from human macrophages to hepato-carcinoma cells and inhibit proliferation JO - J Immunol. VL - 191 UR - https://doi.org/10.4049/jimmunol.1301728 DO - 10.4049/jimmunol.1301728 ID - Aucher2013 ER - TY - JOUR AU - Kenji, T. AU - Yan, I. K. AU - Hiroaki, H. AU - Tushar, P. PY - 2014 DA - 2014// TI - Modulation of hypoxia-signaling pathways by extracellular linc-RoR JO - J Cell Sci VL - 127 UR - https://doi.org/10.1242/jcs.141069 DO - 10.1242/jcs.141069 ID - Kenji2014 ER - TY - JOUR AU - Takahashi, K. e. n. j. i. AU - Yan, I. r. e. n. e. K. AU - Kogure, T. a. k. a. y. u. k. i. AU - Haga, H. i. r. o. a. k. i. AU - Patel, T. u. s. h. a. r. PY - 2014 DA - 2014// TI - Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer JO - FEBS Open Bio VL - 4 UR - https://doi.org/10.1016/j.fob.2014.04.007 DO - 10.1016/j.fob.2014.04.007 ID - Takahashi2014 ER - TY - JOUR AU - Chao, C. AU - Fei, L. AU - Liu, X. AU - Lu, L. AU - Hui, X. AU - Yang, Q. PY - 2017 DA - 2017// TI - NF-kB-regulated exosomal miR-155 promotes the inflammation associated with arsenite carcinogenesis JO - Cancer Lett VL - 388 UR - https://doi.org/10.1016/j.canlet.2016.11.027 DO - 10.1016/j.canlet.2016.11.027 ID - Chao2017 ER - TY - JOUR AU - Fu, X. T. AU - Shi, Y. H. AU - Zhou, J. AU - Peng, Y. F. AU - Liu, W. R. AU - Shi, G. M. PY - 2018 DA - 2018// TI - MicroRNA-30a suppresses autophagy-mediated anoikis resistance and metastasis in hepatocellular carcinoma JO - Cancer Lett VL - 412 ID - Fu2018 ER - TY - JOUR AU - Zhang, Z. AU - Xiao, L. AU - Wei, S. AU - Yue, S. AU - Yang, J. AU - Li, J. PY - 2017 DA - 2017// TI - Loss of exosomal miR-320a from cancer-associated fibroblasts contributes to HCC proliferation and metastasis JO - Cancer Lett VL - 397 UR - https://doi.org/10.1016/j.canlet.2017.03.004 DO - 10.1016/j.canlet.2017.03.004 ID - Zhang2017 ER - TY - JOUR AU - Sudarshana, B. AU - Bhattacharyya, S. N. PY - 2014 DA - 2014// TI - Insulin-like growth factor-1 prevents miR-122 production in neighbouring cells to curtail its intercellular transfer to ensure proliferation of human hepatoma cells JO - Nucleic Acids Res VL - 42 UR - https://doi.org/10.1093/nar/gku346 DO - 10.1093/nar/gku346 ID - Sudarshana2014 ER - TY - JOUR AU - Lou, G. AU - Song, X. AU - Yang, F. AU - Wu, S. AU - Wang, J. AU - Chen, Z. PY - 2015 DA - 2015// TI - Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma JO - J Hematol Oncol. VL - 8 UR - https://doi.org/10.1186/s13045-015-0220-7 DO - 10.1186/s13045-015-0220-7 ID - Lou2015 ER - TY - STD TI - Tang J, Li Y, Liu K, Zhu Q, Yang WH, Xiong LK, et al. Exosomal miR-9-3p suppresses HBGF-5 expression and is a functional biomarker in hepatocellular carcinoma. Minerva Medica. 2018;109. ID - ref72 ER - TY - JOUR AU - Aixue, H. AU - Jie, D. AU - Shaohua, L. AU - Chaonan, W. AU - Hongmei, D. AU - Hui, L. PY - 2015 DA - 2015// TI - Exosomal transfer of vasorin expressed in hepatocellular carcinoma cells promotes migration of human umbilical vein endothelial cells JO - Int J Biol Sci VL - 11 UR - https://doi.org/10.7150/ijbs.11943 DO - 10.7150/ijbs.11943 ID - Aixue2015 ER - TY - STD TI - Yukawa H, Suzuki K, Aoki K, Arimoto T, Yasui T, Kaji N, et al. Imaging of angiogenesis of human umbilical vein endothelial cells by uptake of exosomes secreted from hepatocellular carcinoma cells. Sci Rep. 2018;8. ID - ref74 ER - TY - JOUR AU - Lin, X. u. e. -. J. i. a. AU - Fang, J. i. a. n. -. H. o. n. g. AU - Yang, X. i. a. o. -. J. i. n. g. AU - Zhang, C. h. o. n. g. AU - Yuan, Y. u. n. f. e. i. AU - Zheng, L. i. m. i. n. AU - Zhuang, S. h. i. -. M. e. i. PY - 2018 DA - 2018// TI - Hepatocellular Carcinoma Cell-Secreted Exosomal MicroRNA-210 Promotes Angiogenesis In Vitro and In Vivo JO - Molecular Therapy - Nucleic Acids VL - 11 UR - https://doi.org/10.1016/j.omtn.2018.02.014 DO - 10.1016/j.omtn.2018.02.014 ID - Lin2018 ER - TY - JOUR AU - Conigliaro, A. AU - Costa, V. AU - Dico, A. L. AU - Saieva, L. AU - Buccheri, S. AU - Dieli, F. PY - 2015 DA - 2015// TI - CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA JO - Molecular Cancer. VL - 14 UR - https://doi.org/10.1186/s12943-015-0426-x DO - 10.1186/s12943-015-0426-x ID - Conigliaro2015 ER - TY - JOUR AU - Wu, Z. AU - Zeng, Q. AU - Cao, K. AU - Sun, Y. PY - 2016 DA - 2016// TI - Exosomes: small vesicles with big roles in hepatocellular carcinoma JO - Oncotarget. VL - 7 ID - Wu2016 ER - TY - JOUR AU - Prasanna Kumar, S. AU - Das, S. K. AU - Rachel, G. AU - Dong, C. AU - Jyoti, S. AU - Chadia, R. PY - 2012 DA - 2012// TI - Multifunction protein staphylococcal nuclease domain containing 1 (SND1) promotes tumour angiogenesis in human hepatocellular carcinoma through novel pathway that involves nuclear factor κB and miR-221 JO - J Biol Chem VL - 287 UR - https://doi.org/10.1074/jbc.M111.321646 DO - 10.1074/jbc.M111.321646 ID - Prasanna Kumar2012 ER - TY - JOUR AU - Ning, Z. AU - Wei-Dong, D. AU - Jian-Jun, L. AU - Liang, Z. AU - Xing, W. AU - Yin-Zhe, X. PY - 2015 DA - 2015// TI - STAT3 regulates the migration and invasion of a stem-like subpopulation through microRNA-21 and multiple targets in hepatocellular carcinoma JO - Oncol Reports. VL - 33 UR - https://doi.org/10.3892/or.2015.3710 DO - 10.3892/or.2015.3710 ID - Ning2015 ER - TY - JOUR AU - Zhen, Q. AU - Wu, J. AU - Wu, J. AU - Luo, D. AU - Jiang, C. AU - Ding, Y. PY - 2016 DA - 2016// TI - Exosomes derived from HCC cells induce sorafenib resistance in hepatocellular carcinoma both in vivo and in vitro JO - J Exp Clin Cancer Res VL - 35 UR - https://doi.org/10.1186/s13046-016-0430-z DO - 10.1186/s13046-016-0430-z ID - Zhen2016 ER - TY - STD TI - Karaosmanoğlu O, Banerjee S, Sivas H. Identification of biomarkers associated with partial epithelial to mesenchymal transition in the secretome of slug over-expressing hepatocellular carcinoma cells. Cell Oncol. 2018:1–15. ID - ref81 ER - TY - JOUR AU - Mian, H. AU - Hao, Q. AU - Poon, T. C. W. AU - Siu-Ching, S. AU - Xiaofan, D. AU - Ngai Na, C. PY - 2015 DA - 2015// TI - Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs JO - Carcinogenesis. VL - 36 UR - https://doi.org/10.1093/carcin/bgv081 DO - 10.1093/carcin/bgv081 ID - Mian2015 ER - TY - STD TI - Fang JH, Zhang ZJ, Shang LR, Luo YW, Lin Y, Yuan Y, et al. Hepatoma cell-secreted exosomal microRNA-103 increases vascular permeability and promotes metastasis by targeting junction proteins. Hepatology. 2018. ID - ref83 ER - TY - JOUR AU - Lu, Z. AU - Zuo, B. AU - Jing, R. AU - Gao, X. AU - Rao, Q. AU - Liu, Z. PY - 2017 DA - 2017// TI - Dendritic cell-derived exosomes elicit tumour regression in autochthonous hepatocellular carcinoma mouse models JO - J Hepatol. VL - 67 UR - https://doi.org/10.1016/j.jhep.2017.05.019 DO - 10.1016/j.jhep.2017.05.019 ID - Lu2017 ER - TY - JOUR AU - Lv, L. H. AU - Wan, Y. L. AU - Lin, Y. AU - Zhang, W. AU - Yang, M. AU - Li, G. L. PY - 2012 DA - 2012// TI - Anticancer drugs cause release of exosomes with heat shock proteins from human hepatocellular carcinoma cells that elicit effective natural killer cell antitumour responses in vitro JO - J Biol Chem. VL - 287 UR - https://doi.org/10.1074/jbc.M112.340588 DO - 10.1074/jbc.M112.340588 ID - Lv2012 ER - TY - JOUR AU - Poggio, M. AU - Hu, T. AU - Pai, C. C. AU - Chu, B. AU - Belair, C. D. AU - Chang, A. PY - 2019 DA - 2019// TI - Suppression of exosomal PD-L1 induces systemic anti-tumour immunity and memory JO - Cell. VL - 177 UR - https://doi.org/10.1016/j.cell.2019.02.016 DO - 10.1016/j.cell.2019.02.016 ID - Poggio2019 ER - TY - JOUR AU - Liang, G. AU - Kan, S. AU - Zhu, Y. AU - Feng, S. AU - Feng, W. AU - Gao, S. PY - 2018 DA - 2018// TI - Engineered exosome-mediated delivery of functionally active miR-26a and its enhanced suppression effect in HepG2 cells JO - Int J Nanomedicine. VL - 13 UR - https://doi.org/10.2147/IJN.S154458 DO - 10.2147/IJN.S154458 ID - Liang2018 ER - TY - JOUR AU - Tian, Y. AU - Li, S. AU - Song, J. AU - Ji, T. AU - Zhu, M. AU - Anderson, G. J. PY - 2014 DA - 2014// TI - A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumour therapy JO - Biomaterials. VL - 35 UR - https://doi.org/10.1016/j.biomaterials.2013.11.083 DO - 10.1016/j.biomaterials.2013.11.083 ID - Tian2014 ER - TY - JOUR AU - Takahashi, K. AU - Yan, I. K. AU - Wood, J. AU - Haga, H. AU - Patel, T. PY - 2014 DA - 2014// TI - Involvement of extracellular vesicle long noncoding RNA (linc-VLDLR) in tumour cell responses to chemotherapy JO - Mol Cancer Res VL - 12 UR - https://doi.org/10.1158/1541-7786.MCR-13-0636 DO - 10.1158/1541-7786.MCR-13-0636 ID - Takahashi2014 ER - TY - JOUR AU - Balamurugan, K. PY - 2016 DA - 2016// TI - HIF-1 at the crossroads of hypoxia, inflammation, and cancer JO - Int J Cancer J Int Du Cancer. VL - 138 UR - https://doi.org/10.1002/ijc.29519 DO - 10.1002/ijc.29519 ID - Balamurugan2016 ER - TY - JOUR AU - Bissell, D. M. AU - Roulot, D. AU - George, J. PY - 2001 DA - 2001// TI - Transforming growth factor beta and the liver JO - Hepatology. VL - 34 UR - https://doi.org/10.1053/jhep.2001.28457 DO - 10.1053/jhep.2001.28457 ID - Bissell2001 ER - TY - JOUR AU - Yoshida, K. AU - Matsuzaki, K. AU - Murata, M. AU - Yamaguchi, T. AU - Suwa, K. AU - Okazaki, K. PY - 2018 DA - 2018// TI - Clinico-pathological importance of TGF-β/phospho-smad signaling during human hepatic fibrocarcinogenesis JO - Cancers. VL - 10 UR - https://doi.org/10.3390/cancers10060183 DO - 10.3390/cancers10060183 ID - Yoshida2018 ER - TY - JOUR AU - Seo, W. AU - Eun, H. S. AU - Kim, S. Y. AU - Yi, H. S. AU - Lee, Y. S. AU - Park, S. H. PY - 2016 DA - 2016// TI - Exosome-mediated activation of toll-like receptor 3 in stellate cells stimulates interleukin-17 production by γδ T cells in liver fibrosis JO - Hepatology. VL - 64 UR - https://doi.org/10.1002/hep.28644 DO - 10.1002/hep.28644 ID - Seo2016 ER - TY - JOUR AU - Xu, Q. G. AU - Yu, J. AU - Guo, X. G. AU - Hou, G. J. AU - Yuan, S. X. AU - Yang, Y. PY - 2018 DA - 2018// TI - IL-17A promotes the invasion–metastasis cascade via theAKTpathway in hepatocellular carcinoma JO - Mol Oncol VL - 12 UR - https://doi.org/10.1002/1878-0261.12306 DO - 10.1002/1878-0261.12306 ID - Xu2018 ER - TY - JOUR AU - Liu, Z. AU - Tu, K. AU - Liu, Q. PY - 2016 DA - 2016// TI - Effects of microRNA-30a on migration, invasion and prognosis of hepatocellular carcinoma JO - Febs Lett VL - 588 UR - https://doi.org/10.1016/j.febslet.2014.06.037 DO - 10.1016/j.febslet.2014.06.037 ID - Liu2016 ER - TY - STD TI - Chen J, Yue Y, Shu L, Liu Y, Shu Z, Cao S, et al. MicroRNA-30a ameliorates hepatic fibrosis by inhibiting Beclin1-mediated autophagy. J Cell Mol Med. 2017;21. ID - ref96 ER - TY - JOUR AU - Wei-Chih, T. AU - Paul Wei-Che, H. AU - Tsung-Ching, L. AU - Gar-Yang, C. AU - Ching-Wen, L. AU - Chun-Ming, C. PY - 2010 DA - 2010// TI - MicroRNA-122, a tumour suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma JO - Hepatology. VL - 49 ID - Wei-Chih2010 ER - TY - JOUR AU - Potente, M. AU - Gerhardt, H. AU - Carmeliet, P. PY - 2011 DA - 2011// TI - Basic and therapeutic aspects of angiogenesis JO - Cell. VL - 146 UR - https://doi.org/10.1016/j.cell.2011.08.039 DO - 10.1016/j.cell.2011.08.039 ID - Potente2011 ER - TY - JOUR AU - Samy, L. AU - Jian, X. AU - Rik, D. PY - 2014 DA - 2014// TI - Molecular mechanisms of epithelial-mesenchymal transition JO - Nat Rev Mol Cell Biol VL - 15 UR - https://doi.org/10.1038/nrm3758 DO - 10.1038/nrm3758 ID - Samy2014 ER - TY - JOUR AU - Muh-Hwa, Y. AU - Chih-Li, C. AU - Gar-Yang, C. AU - Shih-Hwa, C. AU - Chien-Wei, S. AU - Teh-Ying, C. PY - 2010 DA - 2010// TI - Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma JO - Hepatology. VL - 50 ID - Muh-Hwa2010 ER - TY - JOUR AU - Roussos, E. T. AU - Condeelis, J. S. AU - Patsialou, A. PY - 2011 DA - 2011// TI - Chemotaxis in cancer JO - Nat Rev Cancer. VL - 11 UR - https://doi.org/10.1038/nrc3078 DO - 10.1038/nrc3078 ID - Roussos2011 ER - TY - JOUR AU - Whittaker, S. AU - Marais, R. AU - Zhu, A. X. PY - 2010 DA - 2010// TI - The role of signaling pathways in the development and treatment of hepatocellular carcinoma JO - Oncogene VL - 29 UR - https://doi.org/10.1038/onc.2010.236 DO - 10.1038/onc.2010.236 ID - Whittaker2010 ER - TY - JOUR AU - Goessler, U. R. AU - Hörmann, K. AU - Riedel, F. PY - 2004 DA - 2004// TI - Tissue engineering with chondrocytes and function of the extracellular matrix (review) JO - Int J Mol Med VL - 13 ID - Goessler2004 ER - TY - JOUR AU - Bazzoni, G. AU - Dejana, E. PY - 2004 DA - 2004// TI - Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis JO - Physiol Rev VL - 84 UR - https://doi.org/10.1152/physrev.00035.2003 DO - 10.1152/physrev.00035.2003 ID - Bazzoni2004 ER - TY - JOUR AU - Robbins, P. D. AU - Morelli, A. E. PY - 2014 DA - 2014// TI - Regulation of immune responses by extracellular vesicles JO - Nat Rev Immunol. VL - 14 UR - https://doi.org/10.1038/nri3622 DO - 10.1038/nri3622 ID - Robbins2014 ER - TY - JOUR AU - Page, D. B. AU - Postow, M. A. AU - Callahan, M. K. AU - Allison, J. P. AU - Wolchok, J. D. PY - 2014 DA - 2014// TI - Immune modulation in cancer with antibodies JO - Annu Rev Med. VL - 65 UR - https://doi.org/10.1146/annurev-med-092012-112807 DO - 10.1146/annurev-med-092012-112807 ID - Page2014 ER - TY - JOUR AU - Yang, T. AU - Martin, P. AU - Fogarty, B. AU - Brown, A. AU - Schurman, K. AU - Phipps, R. PY - 2015 DA - 2015// TI - Exosome delivered anticancer drugs across the blood-brain barrier for brain cancer therapy in Danio rerio JO - Pharm Res. VL - 32 UR - https://doi.org/10.1007/s11095-014-1593-y DO - 10.1007/s11095-014-1593-y ID - Yang2015 ER - TY - JOUR AU - Ha, D. AU - Yang, N. AU - Nadithe, V. PY - 2016 DA - 2016// TI - Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges JO - Acta Pharm Sin B. VL - 6 UR - https://doi.org/10.1016/j.apsb.2016.02.001 DO - 10.1016/j.apsb.2016.02.001 ID - Ha2016 ER - TY - JOUR AU - Vlashi, E. AU - Pajonk, F. PY - 2015 DA - 2015// TI - Cancer stem cells, cancer cell plasticity and radiation therapy JO - Semin Cancer Biol. VL - 31 UR - https://doi.org/10.1016/j.semcancer.2014.07.001 DO - 10.1016/j.semcancer.2014.07.001 ID - Vlashi2015 ER - TY - JOUR AU - Zhaolin, C. AU - Tianlu, S. AU - Lei, Z. AU - Pengli, Z. AU - Mingying, D. AU - Cheng, H. PY - 2016 DA - 2016// TI - Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: a review of the past decade JO - Cancer Lett VL - 370 UR - https://doi.org/10.1016/j.canlet.2015.10.010 DO - 10.1016/j.canlet.2015.10.010 ID - Zhaolin2016 ER -