Skip to main content
Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: High-affinity peptide ligand LXY30 for targeting α3β1 integrin in non-small cell lung cancer

Fig. 2

Characterization of tumor derived exosomes and EVs. The size and morphology of exosomes were evaluated by dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA) (a) and transmission electron microscopy (TEM) (b), respectively. The yield of DNA was 3.4-fold higher in LXY30-enriched exosomes than in S-LXY30-enriched exosomes (3.4 ± 0.7 vs 1.0 ± 0.2 ng/μL, p = 0.014) (c). Driven mutations (EGFR L858R and T790 M in H1975) were detected by PCR and Sanger sequencing in the DNA isolated from LXY30 exosomes (d)

Back to article page