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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: Haploidentical CD19/CD22 bispecific CAR-T cells induced MRD-negative remission in a patient with relapsed and refractory adult B-ALL after haploidentical hematopoietic stem cell transplantation

Fig. 4

Kinetics of presentation of CRS after haplo-TanCAR-T 19/22 cell infusion. a The changes in serum CRP levels and body temperature after haplo-TanCAR-T 19/22 cell infusion. Day 0 is the day of haplo-TanCAR-T 19/22 cell infusion. b Concentrations of listed cytokines in serum obtained from patient at the indicated time points. c Fold changes of listed serum cytokines from baseline (on day 0 before infusion) after haplo-TanCAR-T 19/22 cell infusion. d Serum ALT, AST, e LDH, f prothrombin time and aPTT, g fibrinogen and D-dimer, h serum protein and albumin concentrations are shown at the indicated time points after haplo-TanCAR-T 19/22 cell infusion

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