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Fig. 5 | Journal of Hematology & Oncology

Fig. 5

From: Targeting MYC activity in double-hit lymphoma with MYC and BCL2 and/or BCL6 rearrangements with epigenetic bromodomain inhibitors

Fig. 5

Effect of BET inhibitors on the survival of DHL and THL cells. a–c WT-MYC, SH, DHL, THL, and BCL-2/BCL-6 translocation harboring cell lines were treated with 3 different pharmacological BET bromodomain inhibitors I-BET (a), JQ1 (b), and OTX (c) for 72 h and cell survival was assessed by flow cytometry after annexin V/PI staining. Data represent mean ± SD from three independent experiments. p < 0.05 value was significant for both the concentrations in all the cell lines tested

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