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Table 1 Baseline characteristics of included patients (n = 189)

From: Genomic landscape and its correlations with tumor mutational burden, PD-L1 expression, and immune cells infiltration in Chinese lung squamous cell carcinoma

   Total PD-L1 PD-L1+ P value CD8+ TIL high CD8+ TIL low P value TMB high TMB low P value
   N N % N % N % N % N % N %
Age < 65 105 72 68.57 33 31.43 0.011 82 78.10 23 21.90 0.113 53 50.48 52 49.52 0.948
≥ 65 84 71 84.52 13 15.48   57 67.86 27 32.14   42 50.00 42 50.00  
Sex Male 179 134 74.86 45 25.14 0.480 131 73.18 48 26.82 0.915 91 50.84 88 49.16 0.732
Female 10 9 90.00 1 10.00   8 80.00 2 20.00   4 40.00 6 60.00  
Smoking Never 60 49 81.67 11 18.33 0.190 47 78.33 13 21.67 0.309 25 41.67 35 58.33 0.107
Current/former 129 94 72.87 35 27.13   92 71.32 37 28.68   70 54.26 59 45.74  
ECOG PS 0 140 104 74.29 36 25.71 0.456 105 75.00 35 25.00 0.443 63 45.00 77 55.00 0.014
1 49 39 79.59 10 20.41   34 69.39 15 30.61   32 65.31 17 34.69  
p-Stage I 92 72 78.26 20 21.74 0.417 66 71.74 26 28.26 0.584 45 48.91 47 51.09 0.24
II 54 41 75.93 13 24.07   42 77.78 12 22.22   25 46.30 29 53.70  
III 43 30 69.77 13 30.23   31 72.09 12 27.91   25 58.14 18 41.86  
Pleural invasion Yes 14 13 92.86 1 7.14 0.217 10 71.43 4 28.57 0.898 6 42.86 8 57.14 0.565
No 175 130 74.29 45 25.71   129 73.71 46 26.29   89 50.86 86 49.14  
Vascular invasion Yes 9 6 66.67 3 33.33 0.805 6 66.67 3 33.33 0.927 6 66.67 3 33.33 0.505
No 180 137 76.11 43 23.89   133 73.89 47 26.11   89 49.44 91 50.56  
Differentiation High 10 7 70.00 3 30.00 0.960 7 70.00 3 30.00 0.915 4 40.00 6 60.00 0.732
Intermediate 124 93 75.00 31 25.00   92 74.19 32 25.81   63 50.81 61 49.19  
Low 55 43 78.18 12 21.82   40 72.73 15 27.27   28 50.91 27 49.09  
  1. ECOG PS Eastern Cooperative Oncology Group performance score, p pathological, PD-L1 programmed death ligand 1, TIL tumor-infiltrating lymphocyte, TMB tumor mutation burden