Fig. 1
From: Dual inhibition of IGF-IR and ALK as an effective strategy to eradicate NPM-ALK+ T-cell lymphoma
Combined treatment with PPP and ASP3026 decreases the viability of NPM-ALK+ T cell lymphoma cells. a The combination of PPP and ASP3026 decreased the viability of Karpas 299, SR-786, and DEL cells to a much greater extent than when each of the two drugs was used alone. Results are shown as means ± SD of three independent experiments. b Isobolographic curves of Karpas 299, SR786, and DEL cells show that the data points lie to the left of the envelope of additivity (green area), supporting a synergistic effect of the combination treatment using PPP and ASP3026