Table 1 Characteristics of patients treated with SGN-CD33A by genotype
| Â | CC (n=10)Â | CT/TT (n=10)Â | Total (n=20) | p value |
|---|---|---|---|---|
Gender | Â | Â | Â | 0.361 |
 Female | 5 (50.0%) | 7 (70.0%) | 12 (60.0%) |  |
 Male | 5 (50.0%) | 3 (30.0%) | 8 (40.0%) |  |
Age | Â | Â | Â | 0.418 |
 Mean (range) | 67.3 (27.5-80.0) | 72.3 (42.0 -82.6) | 69.8 (27.5-82.6) |  |
ECOG | Â | Â | Â | 0.160 |
 0 | 2 (20.0%) | 5 (50.0%) | 7 (35.0%) |  |
 1 | 8 (80.0%) | 5 (50.0%) | 13 (65.0%) |  |
Risk group | Â | Â | Â | 0.148 |
 Adverse | 7 (70.0%) | 4 (40.0%) | 11 (55.0%) |  |
 Favorable | 1 (10.0%) | 0 (0.0%) | 1 (5.0%) |  |
 Intermed. | 2 (20.0%) | 6 (60.0%) | 8 (40.0%) |  |
BM blast % | Â | Â | Â | 0.334 |
 Median (Q1, Q3) | 64.0 (43.2, 80.0) | 54.0 (24.0,66.0) | 56.0 (36.0,78.0) |  |
WBC | Â | Â | Â | 0.200 |
 Mean (SD) | 13.6 (17.1) | 5.6 (8.1) | 9.6 (13.7) |  |
 Median (Q1, Q3) | 5.3 (1.7, 16.5) | 1.7 (1.2, 3.8) | 2.5 (1.5, 16.4) |  |
 Range | 0.8 - 51.7 | 0.4 - 23.1 | 0.4 - 51.7 |  |
 IQR | 14.8 | 2.7 | 14.9 |  |
Platelets | Â | Â | Â | 0.913 |
 Mean (SD) | 50.3 (41.2) | 52.4 (43.9) | 51.4 (41.5) |  |
 Median (Q1, Q3) | 34.0 (22.0, 75.0) | 32.0 (21.8,90.8) | 34.0 (19.8,89.5) |  |
 Range | 11.0 - 133.0 | 5.0 - 116.0 | 5.0 - 133.0 |  |
 IQR | 53.0 | 69.0 | 69.8 |  |
De novo | Â | Â | Â | 0.531 |
 Yes | 1 (10.0%) | 2 (20.0%) | 3 (15.0%) |  |
 No | 9 (90.0%) | 8 (80.0%) | 17 (85.0%) |  |
Line of tx | Â | Â | Â | 0.361 |
 1st | 3 (30.0%) | 5 (50.0%) | 8 (40.0%) |  |
 2nd | 7 (70.0%) | 5 (50.0%) | 12 (60.0%) |  |