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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis

Fig. 1

LINC01123 is upregulated in NSCLC tissues and predicts poor prognosis. a The heat map reflects the top 20 upregulated and downregulated lncRNAs in RNA-seq analysis of 3 paired NSCLC tumor and adjacent tissues. b Expression of LINC01123 in 16 paired NSCLC tissues was analyzed by qRT-PCR. c The relative LINC01123 expression score analyzed by FISH in NSCLC tissues and adjacent normal tissues (n = 92). d Relative LINC01123 expression levels in different TNM stages. e Kaplan-Meier analysis showed that elevated expression of LINC01123 was associated with overall survival (OS) in NSCLC patients. f, g Representative FISH images of LINC01123 expression in NSCLC tumor tissues and in different TNM stages (blue, DAPI; red, positive staining). Data shown are mean ± SD (n = 3). (*P < 0.05, **P < 0.01, ***P < 0.001)

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