Table 3 Risk factors for survival and GVHD: Cox regression analysis

 Patient age < 20 years vs. ≥ 20 years

1.863

1.300–2.668

0.001

 HLA 3/6 vs. 5–6/6

4.702

1.161–19.037

0.030

 HLA 3/6 vs. 4/6

1.509

0.906–2.512

0.114

 Patient age < 20 years vs. ≥ 20 years

2.316

1.081–4.962

0.031

 ABO minor mismatch vs. others

2.817

1.438–5.519

0.003

 Mother donor vs. father donor

1.804

1.069–3.044

0.027

 Male to female vs. others

0.433

0.210–0.889

0.023

 Months from diagnosis to transplant ≥ 12 vs. < 12

1.876

1.057–3.328

0.032

 ECOG 2–3 vs. 0–1

3.605

2.028–6.409

0.000

 MNC 6–10 × 10⁸/kg vs. others

0.440

0.249–0.778

0.005

Failure-free survival

 Months from diagnosis to transplant ≥ 12 vs. < 12

1.907

1.124–3.235

0.017

 ECOG 2-3 vs. 0-1

2.388

1.414–4.032

0.001

GVHD-free/relapse-free survival

 ABO minor mismatch vs. others

1.856

1.245–2.765

0.002

 ECOG 2–3 vs. 0–1

1.589

1.016–2.486

0.043

 MNC 6–10 × 10⁸/kg vs. others

0.642

0.433–0.953

0.028