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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Long noncoding RNA GSTM3TV2 upregulates LAT2 and OLR1 by competitively sponging let-7 to promote gemcitabine resistance in pancreatic cancer

Fig. 2

GSTM3TV2 is overexpressed in gemcitabine-resistant pancreatic cancer cells.

a GSTM3TV2 was upregulated in gemcitabine-resistant cells AsPC-1/GR and MIAPaCa-2/GR when validated by quantitative reverse-transcription polymerase chain reaction (qRT-PCR). b In situ hybridization (ISH) analysis showed GSTM3TV2 was overexpressed in gemcitabine-resistant cells AsPC-1/GR and MIAPaCa-2/GR and localized in the cytoplasm. c, d GSTM3TV2 expression was increased when AsPC-1 (c) and MIAPaCa-2 (d) cells stimulated with different concentrations of gemcitabine for 48 h. The data are presented as the mean ± SD (Student’s t test; asterisk indicates P < 0.05)

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Journal of Hematology & Oncology

ISSN: 1756-8722

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