Fig. 4
From: MAGE-A1 in lung adenocarcinoma as a promising target of chimeric antigen receptor T cells
The detection of MAGE-A1 expression in LUAD tissues. a, b qPCR and WB tests in five LUAD and non-cancerous tissue samples showed that the expression of MAGE-A1 in LUAD was elevated compared with that in non-cancerous tissues. *Significant difference of MAGE-A1 expression in LUAD tissue samples compared with non-cancerous tissue samples. p < 0.05. c Detection of MAGE-A1 expression in a tissue microarray (TMA) containing 92 LUAD samples by immunohistochemistry (IHC) analysis. Positive staining of MAGE-A1 was mainly located in the cytoplasm of LUAD cells. d The survival analysis and Kaplan-Meier curve illustrated that positive MAGE-A1 expression (p = 0.022), positive lymph node metastasis (p = 0.001), positive N status (p = 0.002), and advanced TNM stage (p = 0.001) were significantly correlated with a poor prognosis of patients with LUAD