Table 1 Associations of liver stiffness with clinicopathologic characteristics in HCC patients
Liver stiffness (kPa) | P value | |||
|---|---|---|---|---|
≤ 8 | > 8, < 12 | ≥ 12 | ||
No. of patients | 18 | 21 | 35 | |
Age (years) | 52.56 ± 13.84 | 55.81 ± 10.68 | 55.09 ± .10.02 | 0.639 |
Gender (male/female) | 10/8 | 18/3 | 31/4 | 0.013 |
AFP (ng/ml) | 5846 ± 14,403 | 4683 ± 13,468 | 7123 ± 17,313 | 0.412 |
ALB (g/l) | 43.01 ± 3.21 | 44.78 ± 3.53 | 41.37 ± 4.08 | 0.006 |
CB (umol/l) | 4.02 ± 1.60 | 4.77 ± 2.22 | 6.44 ± 5.97 | 0.032 |
ALT (U/l) | 31.18 ± 24.15 | 34.47 ± 22.15 | 42.58 ± 48.63 | 0.245 |
AST (U/l) | 27.43 ± 18.81 | 30.59 ± 17.68 | 39.11 ± 34.43 | 0.035 |
GGT (U/l) | 59.42 ± 54.44 | 79.63 ± 63.29 | 128.34 ± 180.10 | 0.020 |
ALP (U/l) | 84.88 ± 35.79 | 87.14 ± 28.71 | 101.26 ± 75.53 | 0.810 |
APTT (second) | 22.54 ± 11.93 | 20.60 ± 8.93 | 24.84 ± 8.66 | 0.162 |
Tumor size (cm) | 5.68 ± 2.34 | 6.35 ± 4.45 | 7.41 ± 5.06 | 0.616 |
Tumor encapsulation | 0.483 | |||
Yes | 12 | 10 | 19 | |
No | 6 | 11 | 16 | |
Microvascular invasion | 0.615 | |||
Yes | 12 | 11 | 19 | |
No | 6 | 10 | 16 | |
Tumor differentiation | 0.026 | |||
Edmondson I–II | 13 | 18 | 18 | |
III–IV | 5 | 3 | 17 | |
Metavir’s G grade | 0.040 | |||
0–1 | 8 | 8 | 8 | |
2–3 | 10 | 13 | 27 | |
Metavir’s S grade | < 0.001 | |||
0–2 | 12 | 12 | 3 | |
3–4 | 6 | 9 | 32 | |
Recurrence | 0.036 | |||
Yes | 3 | 4 | 16 | |
No | 15 | 17 | 19 | |