TY - JOUR AU - Mulazzani, Matthias AU - Huber, Marion AU - Borchard, Sabine AU - Langer, Sigrid AU - Angele, Barbara AU - Schuh, Elisabeth AU - Meinl, Edgar AU - Dreyling, Martin AU - Birnbaum, Tobias AU - Straube, Andreas AU - Koedel, Uwe AU - von Baumgarten, Louisa PY - 2019 DA - 2019/10/15 TI - APRIL and BAFF: novel biomarkers for central nervous system lymphoma JO - Journal of Hematology & Oncology SP - 102 VL - 12 IS - 1 AB - Early diagnosis of CNS lymphoma (CNSL) is essential for successful therapy of this rapidly progressing brain tumor. However, in patients presenting with focal brain lesions, fast and reliable diagnosis of PCNSL remains a challenge. A proliferation-inducing ligand (APRIL) and B cell activating factor (BAFF) are important factors in the pathophysiology, diagnosis, and prognosis of systemic B cell malignancies. However, their utility as biomarkers for the diagnosis of CNSL and their effects on CNSL cells remain unclear. SN - 1756-8722 UR - https://doi.org/10.1186/s13045-019-0796-4 DO - 10.1186/s13045-019-0796-4 ID - Mulazzani2019 ER -