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Table 2 Sensitivity and specificity of two different CSF cut-off levels of APRIL and BAFF determined by ROC analysis

From: APRIL and BAFF: novel biomarkers for central nervous system lymphoma

Cut-off CSF level

Sensitivity (%)

Specificity (%)

APRIL

 5.41 ng/ml (Youden’s Index)

77.4

87.3

 6.59 ng/ml

62.3

93.7

BAFF

 121 pg/ml (Youden’s Index)

82.4

74.6

 299 pg/ml

47.1

93.7