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Table 2 Sensitivity and specificity of two different CSF cut-off levels of APRIL and BAFF determined by ROC analysis

From: APRIL and BAFF: novel biomarkers for central nervous system lymphoma

Cut-off CSF level Sensitivity (%) Specificity (%)
APRIL
 5.41 ng/ml (Youden’s Index) 77.4 87.3
 6.59 ng/ml 62.3 93.7
BAFF
 121 pg/ml (Youden’s Index) 82.4 74.6
 299 pg/ml 47.1 93.7