Fig. 3From: Tumor-intrinsic signaling pathways: key roles in the regulation of the immunosuppressive tumor microenvironmentTumor-intrinsic signaling as a therapeutic target for cancers. The activation of tumor-intrinsic signaling regulates and promotes the immunosuppressive tumor microenvironment, which includes exclusion and dysfunction of effective immunocytes and recruitment and differentiation of immunosuppressive cells. Therefore, targeting the tumor-intrinsic signaling is a potential strategy for cancer treatmentBack to article page